ABSTRACT: This strategy’s implementation carries out a task in an information system whose completion necessitates a coordinated approach to planning, carrying out, and monitoring in line with the enterprise’s business strategy.A rational, thorough, and holistic strategy for simultaneously designing and implementing systems and system components is called Enterprise Architecture.The unintegrated data in each section, as well as data duplication and information system architecture, makes it necessary to develop a good enterprise architecture to support enterprise business.This research aims to develop an enterprise architecture for a Public Health Center, with a case study at Setiabudi District Public Health Center, South Jakarta, Indonesia.This descriptive research uses the TOGAF-ADM method in designing enterprise architecture The TOGAF method analysis includes Business Architecture, Application Architecture, and Technology Architecture.Primary and secondary data had obtained through observational studies and interviews at the Public Health Center.The data analysis method used in this research is a gap analysis between the target architecture and the current state of the architecture.The main result of this development research presents an enterprise architecture design for a complete and integrated Setiabudi District Public Health Center, South Jakarta.This enterprise architecture study provides significant input and contribution to increasing the effectiveness and efficiency of Setiabudi District Public Health Center services in South Jakarta

KEYWORDS–Enterprise Architecture, Public Health Centers, TOGAF-ADM