Abstract: The current state of educational e-management systems in Nigerian tertiary institutions is a crucial aspect to consider, especially in addressing global educational inequality. By employing a descriptive survey research design, this study aimed to explore the potential applications of Artificial Intelligence (AI) in educational e-management within the Nigerian tertiary educational system. The research focused on the target population from selected tertiary institutions in Lagos State, involving 300 participants including both students and lecturers. The primary data collection tool, “Artificial Intelligence on Educational e-Management Systems in Addressing Global Educational Inequality Questionnaire,” utilized a four-point Likert scale to gather information on the participants’ perceptions. Through the analysis of the collected data using simple percentages and descriptive statistics, the study determined the acceptance or rejection of specific statements related to the potential of AI to address educational inequality in Nigerian tertiary educational institutions. With a high reliability level established through Cronbach’s Alpha testing, the findings revealed that the current state of educational e-management systems in Nigeria is in need of improvement, with many areas lacking efficient systems for managing educational resources and addressing inequality. However, the potential applications of AI in educational e-management within Nigerian tertiary education are vast, offering opportunities for streamlining processes, enhancing access to resources, and personalized learning experiences. Additionally, the potential of AI to address educational inequality within the Nigerian tertiary educational system is also promising. The study recommended that there is need to investigate further the potential of artificial intelligence to address educational inequality in Nigerian tertiary educational institutions. (251 word countKeywords: Artificial Intelligence, educational e-management, tertiary institutions, global inequality and Nigeria